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-Structure paper
Title | Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor. |
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Journal, issue, pages | J. Med. Chem., Vol. 45, Page 1432-1438, Year 2002 |
Publish date | Apr 24, 2001 (structure data deposition date) |
![]() | Dohnalek, J. / Hasek, J. / Duskova, J. / Petrokova, H. / Hradilek, M. / Soucek, M. / Konvalinka, J. / Brynda, J. / Sedlacek, J. / Fabry, M. |
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Methods | X-ray diffraction |
Resolution | 1.83 Å |
Structure data | ![]() PDB-1iiq: |
Chemicals | ![]() ChemComp-0ZR: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / HIV protease / peptidomimetics / HYDROLASE-HYDROLASE INHIBITOR COMPLEX |