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TitleA Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
Journal, issue, pagesJ. Virol., Vol. 76, Page 3482-, Year 2002
Publish dateMar 27, 2002 (structure data deposition date)
AuthorsBressanelli, S. / Tomei, L. / Rey, F.A. / De Francesco, R.
External linksJ. Virol. / PubMed:11884572
MethodsX-ray diffraction
Resolution1.7 - 1.85 Å
Structure data

PDB-1gx5:
Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-1gx6:
Hepatitis C Virus RNA polymerase in complex with UTP and manganese
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-UTP:
URIDINE 5'-TRIPHOSPHATE / UTP*YM

Source
  • hepatitis c virus (isolate bk)
KeywordsTRANSFERASE / POLYPROTEIN / GLYCOPROTEIN / RNA-DIRECTED RNA POLYMERASE / CORE PROTEIN / COAT PROTEIN / ENVELOPE PROTEIN / HELICASE / ATP BINDING / TRANSMEMBRANE / NONSTRUCTURAL PROTEIN / POLYMERASE / RNA-DEPENDENT RNA POLYMERASE / VIRUS REPLICATION / INITIATION

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