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Structure paper

TitleCrystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible region
Journal, issue, pagesBIOCHEM. J., Vol. 362, Page 539-544, Year 2002
Publish dateMay 8, 2001 (structure data deposition date)
AuthorsTomoo, K. / Shen, X. / Okabe, K. / Nozoe, Y. / Fukuhara, S. / Morino, S. / Ishida, T. / Taniguchi, T. / Hasegawa, H. / Terashima, A. ...Tomoo, K. / Shen, X. / Okabe, K. / Nozoe, Y. / Fukuhara, S. / Morino, S. / Ishida, T. / Taniguchi, T. / Hasegawa, H. / Terashima, A. / Sasaki, M. / Katsuya, Y. / Kitamura, K. / Miyoshi, H. / Ishikawa, M. / Miura, K.
External linksBIOCHEM. J. / PubMed:11879179
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1ipb:
CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GPPPA
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1ipc:
CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GTP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GTA:
P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-MGP:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / Initiation factor / Protein biosynthesis

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