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Structure paper

TitleCrystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with cofactors: implications of a flexible loop movement upon substrate binding.
Journal, issue, pagesJ. Biochem., Vol. 131, Page 313-317, Year 2002
Publish dateAug 31, 2001 (structure data deposition date)
AuthorsYajima, S. / Nonaka, T. / Kuzuyama, T. / Seto, H. / Ohsawa, K.
External linksJ. Biochem. / PubMed:11872159
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1jvs:
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase; a target enzyme for antimalarial drugs
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE / reductoisomerase / NADPH

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