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Structure paper

TitleCrystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
Journal, issue, pagesJ. Mol. Biol., Vol. 316, Page 257-264, Year 2002
Publish dateNov 29, 2001 (structure data deposition date)
AuthorsDunten, P. / Belunis, C. / Crowther, R. / Hollfelder, K. / Kammlott, U. / Levin, W. / Michel, H. / Ramsey, G.B. / Swain, A. / Weber, D. / Wertheimer, S.J.
External linksJ. Mol. Biol. / PubMed:11851336
MethodsX-ray diffraction
Resolution1.854 - 2.4 Å
Structure data

PDB-1khb:
PEPCK complex with nonhydrolyzable GTP analog, native data
Method: X-RAY DIFFRACTION / Resolution: 1.854 Å

PDB-1khe:
PEPCK complex with nonhydrolyzable GTP analog, MAD data
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1khf:
PEPCK complex with PEP
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

PDB-1khg:
PEPCK
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-GCP:
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER / GMP-PCP, energy-carrying molecule analogue*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-PEP:
PHOSPHOENOLPYRUVATE

Source
  • homo sapiens (human)
KeywordsLYASE / Gluconeogenesis / P-loop

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