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TitleMutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex.
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 12891-12900, Year 2002
Publish dateAug 3, 2001 (structure data deposition date)
AuthorsLiu, J. / Wang, S. / Hoxie, J.A. / LaBranche, C.C. / Lu, M.
External linksJ. Biol. Chem. / PubMed:11830586
MethodsX-ray diffraction
Resolution1.7 - 2.3 Å
Structure data

PDB-1jpx:
Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Wild type.
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1jq0:
Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Mutant structure.
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • simian immunodeficiency virus
KeywordsVIRAL PROTEIN / GP41 / SIV / HIV-1 / MEMBRANE FUSION / SIX-HELIX BUNDLE / TRIMER-of-HAIRPINS

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