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Structure paper

TitleCrystal structure reveals basis for the inhibitor resistance of human brain trypsin.
Journal, issue, pagesJ. Mol. Biol., Vol. 315, Page 1209-1218, Year 2002
Publish dateMay 15, 2001 (structure data deposition date)
AuthorsKatona, G. / Berglund, G.I. / Hajdu, J. / Graf, L. / Szilagyi, L.
External linksJ. Mol. Biol. / PubMed:11827488
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-1h4w:
Structure of human trypsin IV (brain trypsin)
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-BEN:
BENZAMIDINE

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / SERINE PROTEASE / SIGNAL TRANSDUCTION / INHIBITOR RESISTANCE / ALZHEIMER DISEASE

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