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TitleCrystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling.
Journal, issue, pagesMol. Cell, Vol. 8, Page 1277-1289, Year 2001
Publish dateDec 1, 2001 (structure data deposition date)
AuthorsWu, J.W. / Hu, M. / Chai, J. / Seoane, J. / Huse, M. / Li, C. / Rigotti, D.J. / Kyin, S. / Muir, T.W. / Fairman, R. ...Wu, J.W. / Hu, M. / Chai, J. / Seoane, J. / Huse, M. / Li, C. / Rigotti, D.J. / Kyin, S. / Muir, T.W. / Fairman, R. / Massague, J. / Shi, Y.
External linksMol. Cell / PubMed:11779503
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1khx:
Crystal structure of a phosphorylated Smad2
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / TGF-beta signaling / Smad2 / phosphorylation / receptor kinase signaling / cancer

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