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Structure paper

TitleCrystal structure of the beta Ser178--> Pro mutant of tryptophan synthase. A "knock-out" allosteric enzyme.
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 10653-10660, Year 2002
Publish dateOct 22, 2001 (structure data deposition date)
AuthorsWeyand, M. / Schlichting, I. / Herde, P. / Marabotti, A. / Mozzarelli, A.
External linksJ. Biol. Chem. / PubMed:11756454
MethodsX-ray diffraction
Resolution1.5 - 1.7 Å
Structure data

PDB-1k7x:
CRYSTAL STRUCTURE OF THE BETA-SER178PRO MUTANT OF TRYPTOPHAN SYNTHASE
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-1k8y:
CRYSTAL STRUCTURE OF THE TRYPTOPHAN SYNTHASE BETA-SER178PRO MUTANT COMPLEXED WITH D,L-ALPHA-GLYCEROL-3-PHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-1k8z:
CRYSTAL STRUCTURE OF THE TRYPTOPHAN SYNTHASE BETA-SER178PRO MUTANT COMPLEXED WITH N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-13P:
1,3-DIHYDROXYACETONEPHOSPHATE

ChemComp-IAG:
N-[1H-INDOL-3-YL-ACETYL]GLYCINE ACID

Source
  • salmonella typhimurium (bacteria)
KeywordsLYASE / CARBON-OXYGEN LYASE / TRYPTOPHAN BIOSYNTHESIS / PYRIDOXAL PHOSPHATE

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