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TitleThe antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites.
Journal, issue, pagesNat. Struct. Biol., Vol. 9, Page 57-60, Year 2002
Publish dateOct 29, 2001 (structure data deposition date)
AuthorsLisgarten, J.N. / Coll, M. / Portugal, J. / Wright, C.W. / Aymami, J.
External linksNat. Struct. Biol. / PubMed:11731803
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-1k9g:
Crystal Structure of the Complex of Cryptolepine-d(CCTAGG)2
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-DR1:
5-METHYL-5H-INDOLO[3,2-B]QUINOLINE

ChemComp-HOH:
WATER

KeywordsDNA / DNA intercalator complex

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