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-Structure paper
タイトル | Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. |
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ジャーナル・号・ページ | Proc. Natl. Acad. Sci. USA, Vol. 98, Page 13919-13924, Year 2001 |
掲載日 | 2001年10月18日 (構造データの登録日) |
![]() | Xu, H.E. / Lambert, M.H. / Montana, V.G. / Plunket, K.D. / Moore, L.B. / Collins, J.L. / Oplinger, J.A. / Kliewer, S.A. / Gampe Jr., R.T. / McKee, D.D. ...Xu, H.E. / Lambert, M.H. / Montana, V.G. / Plunket, K.D. / Moore, L.B. / Collins, J.L. / Oplinger, J.A. / Kliewer, S.A. / Gampe Jr., R.T. / McKee, D.D. / Moore, J.T. / Willson, T.M. |
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手法 | X線回折 |
解像度 | 2.3 - 2.5 Å |
構造データ | ![]() PDB-1k74: ![]() PDB-1k7l: |
化合物 | ![]() ChemComp-9CR: ![]() ChemComp-544: ![]() ChemComp-HOH: ![]() ChemComp-YT3: |
由来 |
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![]() | TRANSCRIPTION / The heterodimer of the nuclear receptor ligand binding domains of RXRalpha and PPARgamma bound respectively with 9-cis retinoic acid and GW409544 and coactivator peptides / The 2.5 Angstrom resolution crystal structure of the human PPARalpha ligand binding domain bound with GW409544 and a coactivator peptide |