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Structure paper

TitleStructural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.
Journal, issue, pagesNature, Vol. 413, Page 814-821, Year 2001
Publish dateMar 6, 2002 (structure data deposition date)
AuthorsSchlunzen, F. / Zarivach, R. / Harms, J. / Bashan, A. / Tocilj, A. / Albrecht, R. / Yonath, A. / Franceschi, F.
External linksNature / PubMed:11677599
MethodsX-ray diffraction
Resolution3.1 - 3.8 Å
Structure data

PDB-1j5a:
STRUCTURAL BASIS FOR THE INTERACTION OF ANTIBIOTICS WITH THE PEPTIDYL TRANSFERASE CENTER IN EUBACTERIA
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-1jzx:
Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Center in Eubacteria
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-1jzy:
Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Center in Eubacteria
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-1jzz:
Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Center in Eubacteria
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

PDB-1k01:
Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Center in Eubacteria
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-CTY:
CLARITHROMYCIN

ChemComp-MG:
Unknown entry

ChemComp-CLY:
CLINDAMYCIN / antibiotic*YM

ChemComp-ERY:
ERYTHROMYCIN A / antibiotic*YM

ChemComp-ROX:
ROXITHROMYCIN

ChemComp-CLM:
CHLORAMPHENICOL / antibiotic*YM

Source
  • deinococcus radiodurans (radioresistant)
KeywordsRIBOSOME / 50S / 23S / 5S / ANTIBIOTICS / CLARITHROMYCIN / PEPTIDYL TRANSFERASE CENTER / Clindamycin / Erythromycin / Roxithromycin / Chloramphenicol

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