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Structure paper

TitleStructural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase.
Journal, issue, pagesJ. Biol. Chem., Vol. 276, Page 47387-47393, Year 2001
Publish dateSep 17, 2001 (structure data deposition date)
AuthorsNakama, T. / Nureki, O. / Yokoyama, S.
External linksJ. Biol. Chem. / PubMed:11584022
MethodsX-ray diffraction
Resolution2.5 - 3 Å
Structure data

PDB-1jzq:
Isoleucyl-tRNA synthetase Complexed with Isoleucyl-adenylate analogue
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1jzs:
Isoleucyl-tRNA synthetase Complexed with mupirocin
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ILA:
N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE

ChemComp-MRC:
MUPIROCIN / antibiotic*YM

Source
  • thermus thermophilus (bacteria)
KeywordsLIGASE / aminoacyl-tRNA synthetase / RIKEN Structural Genomics/Proteomics Initiative / RSGI / Structural Genomics

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