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TitleStructural basis for SRY-dependent 46-X,Y sex reversal: modulation of DNA bending by a naturally occurring point mutation.
Journal, issue, pagesJ. Mol. Biol., Vol. 312, Page 481-499, Year 2001
Publish dateJul 23, 2001 (structure data deposition date)
AuthorsMurphy, E.C. / Zhurkin, V.B. / Louis, J.M. / Cornilescu, G. / Clore, G.M.
External linksJ. Mol. Biol. / PubMed:11563911
MethodsNMR (solution)
Structure data

PDB-1j46:
3D Solution NMR Structure of the Wild Type HMG-BOX Domain of the Human Male Sex Determining Factor Sry Complexed to DNA
Method: SOLUTION NMR

PDB-1j47:
3D Solution NMR Structure of the M9I Mutant of the HMG-Box Domain of the Human Male Sex Determining Factor SRY Complexed to DNA
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/DNA / MALE SEX DETERMINING FACTOR / SRY / SEX-REVERSAL MUTATION / DNA BENDING MUTANT / DIPOLAR COUPLINGS / MULTIDIMENSIONAL NMR / TRANSCRIPTION-DNA COMPLEX

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