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TitleA DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability
Journal, issue, pagesBiochemistry, Vol. 40, Page 11372-11381, Year 2001
Publish dateJul 22, 2001 (structure data deposition date)
AuthorsShah, A.M. / Conn, D.A. / Li, S.-X. / Capaldi, A. / Jaeger, J. / Sweasy, J.B.
External linksBiochemistry / PubMed:11560485
MethodsX-ray diffraction
Resolution2.35 Å
Structure data

PDB-1jn3:
FIDELITY PROPERTIES AND STRUCTURE OF M282L MUTATOR MUTANT OF DNA POLYMERASE: SUBTLE STRUCTURAL CHANGES INFLUENCE THE MECHANISM OF NUCLEOTIDE DISCRIMINATION
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsTRANSFERASE / DNA POLYMERASE BETA (Fragment) / mutant / NUCLEOTIDE DISCRIMINATION

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