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-Structure paper
Title | Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 11, Page 2241-2244, Year 2001 |
Publish date | Feb 12, 2001 (structure data deposition date) |
![]() | Seefeld, M.A. / Miller, W.H. / Newlander, K.A. / Burgess, W.J. / Payne, D.J. / Rittenhouse, S.F. / Moore, T.D. / DeWolf, W.E. / Keller, P.M. / Qiu, X. ...Seefeld, M.A. / Miller, W.H. / Newlander, K.A. / Burgess, W.J. / Payne, D.J. / Rittenhouse, S.F. / Moore, T.D. / DeWolf, W.E. / Keller, P.M. / Qiu, X. / Janson, C.A. / Vaidya, K. / Fosberry, A.P. / Smyth, M.G. / Jaworski, D.D. / Slater-Radosti, C. / Huffman, W.F. |
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Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | ![]() PDB-1i30: |
Chemicals | ![]() ChemComp-NAD: ![]() ChemComp-826: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / enoyl reductase / acp / antibiotic |