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-Structure paper
Title | Biochemical and structural assessment of the 1-N-azasugar GalNAc-isofagomine as a potent family 20 beta-N-acetylhexosaminidase inhibitor. |
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Journal, issue, pages | J. Biol. Chem., Vol. 276, Page 42131-42137, Year 2001 |
Publish date | May 30, 2001 (structure data deposition date) |
Authors | Mark, B.L. / Vocadlo, D.J. / Zhao, D. / Knapp, S. / Withers, S.G. / James, M.N. |
External links | J. Biol. Chem. / PubMed:11522797 |
Methods | X-ray diffraction |
Resolution | 1.75 Å |
Structure data | PDB-1jak: |
Chemicals | ChemComp-SO4: ChemComp-CL: ChemComp-IFG: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / glycoside hydrolase / family 20 / Beta-N-acetylhexosaminidase / substrate-assisted catalysis / alpha/beta barrel / isofagomine inhibitor complex |