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TitleStructure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.
Journal, issue, pagesJ. Biol. Chem., Vol. 276, Page 42091-42098, Year 2001
Publish dateMay 23, 2001 (structure data deposition date)
AuthorsNahoum, V. / Gangloff, A. / Legrand, P. / Zhu, D.W. / Cantin, L. / Zhorov, B.S. / Luu-The, V. / Labrie, F. / Breton, R. / Lin, S.X.
External linksJ. Biol. Chem. / PubMed:11514561
MethodsX-ray diffraction
Resolution1.25 Å
Structure data

PDB-1j96:
Human 3alpha-HSD type 3 in Ternary Complex with NADP and Testosterone
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-TES:
TESTOSTERONE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / Aldo-keto reductase / steroid metabolism

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