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Structure paper

TitleSelection, Characterization and X-Ray Structure of Anti-Ampicillin Single-Chain Fv Fragments from Phage-Displayed Murine Antibody Libraries
Journal, issue, pagesJ. Mol. Biol., Vol. 309, Page 671-, Year 2001
Publish dateFeb 14, 2001 (structure data deposition date)
AuthorsBurmester, J. / Spinelli, S. / Pugliese, L. / Krebber, A. / Honegger, A. / Jung, S. / Schimmele, B. / Cambillau, C. / Pluckthun, A.
External linksJ. Mol. Biol. / PubMed:11397088
MethodsX-ray diffraction
Resolution2.4 - 2.75 Å
Structure data

PDB-1h8o:
Three-dimensional structure of anti-ampicillin single chain Fv fragment.
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-1h8s:
Three-dimensional structure of anti-ampicillin single chain Fv fragment complexed with the hapten.
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1i3g:
CRYSTAL STRUCTURE OF AN AMPICILLIN SINGLE CHAIN FV, FORM 1, FREE
Method: X-RAY DIFFRACTION / Resolution: 2.44 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-AIC:
(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC / antibiotic*YM

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

Source
  • mus musculus (house mouse)
KeywordsANTIBODY / FV FRAGMENT / ANTI-AMPICILLIN / ANTI-AMPICILLIN ANTIBODIES / ANTIBIOTIC / ANTIBODY FV FRAGMENT

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