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Structure paper

TitleSuccinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase.
Journal, issue, pagesJ. Biol. Chem., Vol. 276, Page 31913-31918, Year 2001
Publish dateJul 4, 2001 (structure data deposition date)
AuthorsToney, J.H. / Hammond, G.G. / Fitzgerald, P.M. / Sharma, N. / Balkovec, J.M. / Rouen, G.P. / Olson, S.H. / Hammond, M.L. / Greenlee, M.L. / Gao, Y.D.
External linksJ. Biol. Chem. / PubMed:11390410
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1jje:
IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A BIARYL SUCCINIC ACID INHIBITOR (11)
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1jjt:
IMP-1 METALLO BETA-LACTAMASE FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH A BIARYL SUCCINIC ACID INHIBITOR (1)
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-BYS:
2-BENZO[1,3]DIOXOL-5-YLMETHYL-3-BENZYL-SUCCINIC ACID

ChemComp-HOH:
WATER

ChemComp-BDS:
2,3-BIS-BENZO[1,3]DIOXOL-5-YLMETHYL-SUCCINIC ACID

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / METALLO-BETA-LACTAMASE INHIBITOR / SUCCINIC ACID INHIBITOR / IMP-1 METALLO-BETA-LACTAMASE

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