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Structure paper

TitleThe structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Journal, issue, pagesNature, Vol. 411, Page 215-219, Year 2001
Publish dateFeb 20, 2001 (structure data deposition date)
AuthorsTarricone, C. / Xiao, B. / Justin, N. / Walker, P.A. / Rittinger, K. / Gamblin, S.J. / Smerdon, S.J.
External linksNature / PubMed:11346801
MethodsX-ray diffraction
Resolution2.5 - 2.8 Å
Structure data

PDB-1i49:
CRYSTAL STRUCTURE ANALYSIS OF ARFAPTIN
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1i4d:
CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP COMPLEXED WITH ARFAPTIN (P21)
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1i4l:
CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41)
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-1i4t:
CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / coiled coil / G-protein / complex / GTPase

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