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-Structure paper
Title | Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action. |
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Journal, issue, pages | Biochemistry, Vol. 40, Page 5642-5654, Year 2001 |
Publish date | Nov 10, 2000 (structure data deposition date) |
![]() | Bleasdale, J.E. / Ogg, D. / Palazuk, B.J. / Jacob, C.S. / Swanson, M.L. / Wang, X.Y. / Thompson, D.P. / Conradi, R.A. / Mathews, W.R. / Laborde, A.L. ...Bleasdale, J.E. / Ogg, D. / Palazuk, B.J. / Jacob, C.S. / Swanson, M.L. / Wang, X.Y. / Thompson, D.P. / Conradi, R.A. / Mathews, W.R. / Laborde, A.L. / Stuchly, C.W. / Heijbel, A. / Bergdahl, K. / Bannow, C.A. / Smith, C.W. / Svensson, C. / Liljebris, C. / Schostarez, H.J. / May, P.D. / Stevens, F.C. / Larsen, S.D. |
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Methods | X-ray diffraction |
Resolution | 1.8 - 2.2 Å |
Structure data | ![]() PDB-1g7f: ![]() PDB-1g7g: |
Chemicals | ![]() ChemComp-INZ: ![]() ChemComp-HOH: ![]() ChemComp-INX: |
Source |
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![]() | HYDROLASE / HYDROLASE (PHOSPHORYLATION) / TYROSINE PHOSPHATASE / INHIBITOR / COMPLEX / HYDROLASE (PHOSPHORYLASE) |