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Title | Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein. |
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Journal, issue, pages | J. Biol. Chem., Vol. 276, Page 27548-27554, Year 2001 |
Publish date | Feb 6, 2001 (structure data deposition date) |
Authors | Ikuta, M. / Kamata, K. / Fukasawa, K. / Honma, T. / Machida, T. / Hirai, H. / Suzuki-Takahashi, I. / Hayama, T. / Nishimura, S. |
External links | J. Biol. Chem. / PubMed:11335721 |
Methods | X-ray diffraction |
Resolution | 2 - 2.8 Å |
Structure data | PDB-1gih: PDB-1gii: PDB-1gij: |
Chemicals | ChemComp-1PU: ChemComp-HOH: ChemComp-2PU: |
Source |
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Keywords | TRANSFERASE / protein kinase / cell cycle / inhibition |