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Structure paper

TitleHow the Pseudomonas Aeruginosa Exos Toxin Downregulates Rac
Journal, issue, pagesNat. Struct. Biol., Vol. 8, Page 23-, Year 2001
Publish dateNov 18, 2000 (structure data deposition date)
AuthorsWurtele, M. / Wolf, E. / Pederson, K.J. / Buchwald, G. / Ahmadian, M.R. / Barbieri, J.T. / Wittinghofer, A.
External linksNat. Struct. Biol. / PubMed:11135665
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1he1:
Crystal structure of the complex between the GAP domain of the Pseudomonas aeruginosa ExoS toxin and human Rac
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-AF3:
ALUMINUM FLUORIDE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (bacteria)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / SIGNALLING COMPLEX / EXOS / RAC / PSEUDOMONAS AERUGINOSA / GAP / TOXIN / VIRULENCE FACTOR / TRANSITION STATE / PROTEIN-PROTEIN COMPLEX / GTPASE / SIGNAL TRANSDUCTION

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