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Structure paper

TitleCrystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase.
Journal, issue, pagesJ. Biol. Chem., Vol. 276, Page 10330-10337, Year 2001
Publish dateDec 12, 2000 (structure data deposition date)
AuthorsMark, B.L. / Vocadlo, D.J. / Knapp, S. / Triggs-Raine, B.L. / Withers, S.G. / James, M.N.
External linksJ. Biol. Chem. / PubMed:11124970
MethodsX-ray diffraction
Resolution2.1 - 2.2 Å
Structure data

PDB-1hp4:
CRYSTAL STRUCTURE OF STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1hp5:
STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE COMPLEXED WITH INTERMEDIATE ANALOUGE NAG-THIAZOLINE
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NGT:
3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL

Source
  • streptomyces plicatus (bacteria)
KeywordsHYDROLASE / glycosyl hydrolase / hexosaminidase / Streptomyces plicatus / family 20 / TIM barrel / substrate assisted catalysis

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