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Structure paper

TitleCatalytic Center Assembly of Hppk as Revealed by the Crystal Structure of a Ternary Complex at 1.25 A Resolution
Journal, issue, pagesStructure, Vol. 8, Page 1049-1058, Year 2000
Publish dateJul 16, 2003 (structure data deposition date)
AuthorsBlaszczyk, J. / Shi, G. / Yan, H. / Ji, X.
External linksStructure / PubMed:11080626
MethodsX-ray diffraction
Resolution1.25 Å
Structure data

PDB-1q0n:
CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE FROM E. COLI WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-APC:
DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER / AMP-CPP, energy-carrying molecule analogue*YM

ChemComp-PH2:
2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / PYROPHOSPHOKINASE / PYROPHOSPHORYL TRANSFER / FOLATE / HPPK / PTERIN / 6-HYDROXYMETHYL-7 / 8-DIHYDROPTERIN / TERNARY COMPLEX / SUBSTRATE SPECIFICITY / ANTIMICROBIAL AGENT / DRUG DESIGN

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