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TitleIdentification of novel inhibitors of urokinase via NMR-based screening.
Journal, issue, pagesJ. Med. Chem., Vol. 43, Page 3862-3866, Year 2000
Publish dateSep 19, 2000 (structure data deposition date)
AuthorsHajduk, P.J. / Boyd, S. / Nettesheim, D. / Nienaber, V. / Severin, J. / Smith, R. / Davidson, D. / Rockway, T. / Fesik, S.W.
External linksJ. Med. Chem. / PubMed:11052791
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-1fv9:
Crystal structure of human microurokinase in complex with 2-amino-5-hydroxy-benzimidazole
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-172:
2-AMINO-5-HYDROXY-BENZIMIDAZOLE

Source
  • homo sapiens (human)
KeywordsBLOOD CLOTTING / Plasminogen activation

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