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Structure paper

TitleStructural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases.
Journal, issue, pagesJ. Biol. Chem., Vol. 275, Page 41287-41298, Year 2000
Publish dateAug 17, 2000 (structure data deposition date)
AuthorsVallee, F. / Karaveg, K. / Herscovics, A. / Moremen, K.W. / Howell, P.L.
External linksJ. Biol. Chem. / PubMed:10995765
MethodsX-ray diffraction
Resolution1.75 - 2.38 Å
Structure data

PDB-1fmi:
CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1fo2:
CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-1fo3:
CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH KIFUNENSINE
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-DMJ:
1-DEOXYMANNOJIRIMYCIN

ChemComp-KIF:
KIFUNENSINE / inhibitor, alkaloid*YM

Source
  • homo sapiens (human)
KeywordsHYDROLASE / alpha-alpha7 barrel

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