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Structure paper

TitleThe three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins.
Journal, issue, pagesJ. Mol. Biol., Vol. 302, Page 853-872, Year 2000
Publish dateApr 13, 2000 (structure data deposition date)
AuthorsGuddat, L.W. / Shan, L. / Broomell, C. / Ramsland, P.A. / Fan, Z. / Anchin, J.M. / Linthicum, D.S. / Edmundson, A.B.
External linksJ. Mol. Biol. / PubMed:10993728
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1etz:
THE THREE-DIMENSIONAL STRUCTURE OF AN ANTI-SWEETENER FAB, NC10.14, SHOWS THE EXTENT OF STRUCTURAL DIVERSITY IN ANTIGEN RECOGNITION BY IMMUNOGLOBULINS
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-GAS:
N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Anti-sweetener Fab / Antigen-antibody / Complex / Receptor Mimicry / Antigen Recognition

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