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TitleCharged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.
Journal, issue, pagesEMBO J., Vol. 19, Page 3530-3541, Year 2000
Publish dateJun 7, 2000 (structure data deposition date)
AuthorsYoon, C. / Johnston, S.C. / Tang, J. / Stahl, M. / Tobin, J.F. / Somers, W.S.
External linksEMBO J. / PubMed:10899108
MethodsX-ray diffraction
Resolution2.5 - 2.8 Å
Structure data

PDB-1f42:
THE P40 DOMAIN OF HUMAN INTERLEUKIN-12
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1f45:
HUMAN INTERLEUKIN-12
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-MNB:
5-MERCAPTO-2-NITRO-BENZOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE / CYTOKINE/CYTOKINE / interleukin / CYTOKINE-CYTOKINE COMPLEX

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