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Structure paper

TitleCrystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 97, Page 8233-8238, Year 2000
Publish dateApr 28, 2000 (structure data deposition date)
AuthorsChen, J.C. / Krucinski, J. / Miercke, L.J. / Finer-Moore, J.S. / Tang, A.H. / Leavitt, A.D. / Stroud, R.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:10890912
MethodsX-ray diffraction
Resolution1.6 - 2.8 Å
Structure data

PDB-1ex4:
HIV-1 INTEGRASE CATALYTIC CORE AND C-TERMINAL DOMAIN
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1exq:
CRYSTAL STRUCTURE OF THE HIV-1 INTEGRASE CATALYTIC CORE DOMAIN
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-CPS:
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE / detergent*YM

ChemComp-HOH:
WATER

ChemComp-CD:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • human immunodeficiency virus 1
KeywordsVIRAL PROTEIN / SH3-like domain / nonspecific DNA binding beta sheet / cis-proline / HIV-1 integrase / polynucleotidyl transferase / DNA-binding protein / DD35E

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