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Structure paper

TitleThe first structure of UDP-glucose dehydrogenase reveals the catalytic residues necessary for the two-fold oxidation.
Journal, issue, pagesBiochemistry, Vol. 39, Page 7012-7023, Year 2000
Publish dateDec 9, 1999 (structure data deposition date)
AuthorsCampbell, R.E. / Mosimann, S.C. / van De Rijn, I. / Tanner, M.E. / Strynadka, N.C.
External linksBiochemistry / PubMed:10841783
MethodsX-ray diffraction
Resolution1.8 - 2.31 Å
Structure data

PDB-1dli:
THE FIRST STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE (UDPGDH) REVEALS THE CATALYTIC RESIDUES NECESSARY FOR THE TWO-FOLD OXIDATION
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

PDB-1dlj:
THE FIRST STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE (UDPGDH) REVEALS THE CATALYTIC RESIDUES NECESSARY FOR THE TWO-FOLD OXIDATION
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-UDX:
URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NAI:
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

ChemComp-UGA:
URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID

Source
  • streptococcus pyogenes (bacteria)
KeywordsOXIDOREDUCTASE / ROSSMANN FOLD / TERNARY COMPLEX / CRYSTALLOGRAPHIC DIMER

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