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TitleAlteration of a Single Amino Acid in Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha) Generates a PPAR delta Phenotype
Journal, issue, pagesMOL. ENDOCRINOL., Vol. 14, Page 733-740, Year 2000
Publish dateNov 16, 2004 (structure data deposition date)
AuthorsTakada, I. / Yu, R.T. / Xu, H.E. / Lambert, M.H. / Montana, V.G. / Kliewer, S.A. / Evans, R.M. / Umesono, K.
External linksMOL. ENDOCRINOL. / PubMed:10809235
MethodsX-ray diffraction
Resolution2.65 Å
Structure data

PDB-1y0s:
Crystal structure of PPAR delta complexed with GW2331
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-IOD:
IODIDE ION

ChemComp-331:
(2S)-2-(4-[2-(3-[2,4-DIFLUOROPHENYL]-1-HEPTYLUREIDO)ETHYL]PHENOXY)-2-METHYLBUTYRIC ACID

ChemComp-B7G:
heptyl beta-D-glucopyranoside

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR RECEPTOR / PPAR / HORMONE-GROWTH FACTOR RECEPTOR COMPLEX

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