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Structure paper

TitleStructural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex
Journal, issue, pagesNature, Vol. 404, Page 518-, Year 2000
Publish dateDec 20, 1999 (structure data deposition date)
AuthorsFuentes-Prior, P. / Iwanaga, Y. / Huber, R. / Pagila, R. / Rumennik, G. / Seto, M. / Morser, J. / Light, D.R. / Bode, W.
External linksNature / PubMed:10761923
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1dx5:
Crystal structure of the thrombin-thrombomodulin complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-FMT:
FORMIC ACID

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-0GJ:
L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / SERINE PROTEINASE / EGF-LIKE DOMAINS / ANTICOAGULANT COMPLEX / ANTIFIBRINOLYTIC COMPLEX / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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