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TitleMapping sonic hedgehog-receptor interactions by steric interference.
Journal, issue, pagesJ. Biol. Chem., Vol. 275, Page 10995-11001, Year 2000
Publish dateMar 5, 2010 (structure data deposition date)
AuthorsPepinsky, R.B. / Rayhorn, P. / Day, E.S. / Dergay, A. / Williams, K.P. / Galdes, A. / Taylor, F.R. / Boriack-Sjodin, P.A. / Garber, E.A.
External linksJ. Biol. Chem. / PubMed:10753901
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-3m1n:
Crystal structure of Human Sonic Hedgehog N-terminal domain
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Hedgehog proteins / signaling / zinc ions / sulfate ions / autocatalytic cleavage / cell membrane / developmental protein / glycoprotein / holoprosencephaly / hydrolase / lipoprotein / membrane / microphthalmia / palmitate / protease / secreted

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