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Structure paper

TitleAn open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism.
Journal, issue, pagesJ. Biol. Chem., Vol. 275, Page 18311-18317, Year 2000
Publish dateDec 27, 1999 (structure data deposition date)
AuthorsShimizu, T. / Ihara, K. / Maesaki, R. / Kuroda, S. / Kaibuchi, K. / Hakoshima, T.
External linksJ. Biol. Chem. / PubMed:10748207
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1dpf:
CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION/SIGNALING PROTEIN / PROTEIN RHOA-GDP COMPLEX / GENE REGULATION-SIGNALING PROTEIN COMPLEX

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