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-Structure paper
Title | Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation. |
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Journal, issue, pages | J. Biol. Chem., Vol. 275, Page 15265-15270, Year 2000 |
Publish date | Mar 6, 2000 (structure data deposition date) |
Authors | Argiriadi, M.A. / Morisseau, C. / Goodrow, M.H. / Dowdy, D.L. / Hammock, B.D. / Christianson, D.W. |
External links | J. Biol. Chem. / PubMed:10747889 |
Methods | X-ray diffraction |
Resolution | 3 - 3.1 Å |
Structure data | PDB-1ek1: PDB-1ek2: |
Chemicals | ChemComp-CIU: ChemComp-HOH: ChemComp-CDU: |
Source |
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Keywords | HYDROLASE / HOMODIMER / ALPHA/BETA HYDROLASE FOLD / DISUBSTITUTED UREA INHIBITOR |