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Structure paper

TitleCocrystallization of a mutant aspartate aminotransferase with a C5-dicarboxylic substrate analog: structural comparison with the enzyme-C4-dicarboxylic analog complex.
Journal, issue, pagesJ. Biochem. (Tokyo), Vol. 127, Page 337-343, Year 2000
Publish dateSep 2, 1999 (structure data deposition date)
AuthorsOue, S. / Okamoto, A. / Yano, T. / Kagamiyama, H.
External linksPubMed:10731702
MethodsX-ray diffraction
Resolution2.4 - 2.5 Å
Structure data

PDB-1czc:
ASPARTATE AMINOTRANSFERASE MUTANT ATB17/139S/142N WITH GLUTARIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1cze:
ASPARTATE AMINOTRANSFERASE MUTANT ATB17/139S/142N WITH SUCCINIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-GUA:
GLUTARIC ACID

ChemComp-HOH:
WATER

ChemComp-SIN:
SUCCINIC ACID

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / ASPARTATE AMINOTRANSFERASE / SUBSTRATE SPECIFICITY

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