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TitleX-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
Journal, issue, pagesJ. Mol. Biol., Vol. 296, Page 521-533, Year 2000
Publish dateDec 21, 1999 (structure data deposition date)
AuthorsChen, Z. / Yan, Y. / Munshi, S. / Li, Y. / Zugay-Murphy, J. / Xu, B. / Witmer, M. / Felock, P. / Wolfe, A. / Sardana, V. ...Chen, Z. / Yan, Y. / Munshi, S. / Li, Y. / Zugay-Murphy, J. / Xu, B. / Witmer, M. / Felock, P. / Wolfe, A. / Sardana, V. / Emini, E.A. / Hazuda, D. / Kuo, L.C.
External linksJ. Mol. Biol. / PubMed:10669606
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-1c6v:
SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • simian immunodeficiency virus
KeywordsDNA BINDING PROTEIN / DNA INTEGRATION

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