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Structure paper

TitleDNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected
Journal, issue, pagesNature, Vol. 403, Page 451-456, Year 2000
Publish dateNov 13, 1999 (structure data deposition date)
AuthorsMol, C.D. / Izumi, T. / Mitra, S. / Tainer, J.A.
External linksNature / PubMed:10667800
MethodsX-ray diffraction
Resolution2.65 - 3 Å
Structure data

PDB-1de8:
HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) BOUND TO ABASIC DNA
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-1de9:
HUMAN APE1 ENDONUCLEASE WITH BOUND ABASIC DNA AND MN2+ ION
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1dew:
CRYSTAL STRUCTURE OF HUMAN APE1 BOUND TO ABASIC DNA
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsLYASE/DNA / ENZYME:DNA COMPLEX / DNA REPAIR / ABASIC SITE / LYASE-DNA COMPLEX / DNA REPAIR ABASIC SITE / AP ENDONUCLEASE

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