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TitleSequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(CTTTTGCAAAAG)(2).
Journal, issue, pagesNucleic Acids Res., Vol. 28, Page 728-735, Year 2000
Publish dateJun 24, 1999 (structure data deposition date)
AuthorsGavathiotis, E. / Sharman, G.J. / Searle, M.S.
External linksNucleic Acids Res. / PubMed:10637324
MethodsNMR (solution)
Structure data

PDB-1qsx:
SOLUTION NMR STRUCTURE OF THE 2:1 HOECHST 33258-D(CTTTTGCAAAAG)2 COMPLEX
Method: SOLUTION NMR

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HT:
2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE

KeywordsDNA / DRUG-DNA COMPLEX / HOECHST 33258 / DEOXYRIBONUCLEIC ACID / MINOR GROOVE RECOGNITION / DOUBLE HELIX / NMR SPECTROSCOPY

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