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Structure paper

TitleCrystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV.
Journal, issue, pagesVirology, Vol. 265, Page 153-163, Year 1999
Publish dateApr 15, 1999 (structure data deposition date)
AuthorsBergmann, E.M. / Cherney, M.M. / Mckendrick, J. / Frormann, S. / Luo, C. / Malcolm, B.A. / Vederas, J.C. / James, M.N.
External linksVirology / PubMed:10603326
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1qa7:
CRYSTAL COMPLEX OF THE 3C PROTEINASE FROM HEPATITIS A VIRUS WITH ITS INHIBITOR AND IMPLICATIONS FOR THE POLYPROTEIN PROCESSING IN HAV
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-IVF:
N-(iodoacetyl)-L-valyl-L-phenylalaninamide

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • hepatitis a virus
Keywordshydrolase/hydrolase inhibitor / CHYMOTRYPSIN-LIKE CYSTEINE PROTEINASE VIRAL PROTEASE P'-SITE INHIBITOR / HYDROLASE / hydrolase-hydrolase inhibitor complex

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