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TitleCrystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 99, Page 323-334, Year 1999
Publish dateOct 11, 1999 (structure data deposition date)
AuthorsLee, J.O. / Yang, H. / Georgescu, M.M. / Di Cristofano, A. / Maehama, T. / Shi, Y. / Dixon, J.E. / Pandolfi, P. / Pavletich, N.P.
External linksCell(Cambridge,Mass. ) / PubMed:10555148
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1d5r:
Crystal Structure of the PTEN Tumor Suppressor
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / C2 DOMAIN / PHOSPHOTIDYLINOSITOL / PHOSPHATASE

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