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TitleThe atomic-resolution structure of human caspase-8, a key activator of apoptosis.
Journal, issue, pagesStructure Fold. Des., Vol. 7, Page 1135-1143, Year 1999
Publish dateJun 28, 1999 (structure data deposition date)
AuthorsWatt, W. / Koeplinger, K.A. / Mildner, A.M. / Heinrikson, R.L. / Tomasselli, A.G. / Watenpaugh, K.D.
External linksStructure Fold. Des. / PubMed:10508785
MethodsX-ray diffraction
Resolution1.2 Å
Structure data

PDB-1qtn:
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-8 WITH THE TETRAPEPTIDE INHIBITOR ACE-IETD-ALDEHYDE
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

Chemicals

ChemComp-DTD:
DITHIANE DIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / APOPTOSIS / DITHIANE-DIOL / CASPASE / CYSTEINE-PROTEASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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