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TitleStructural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain.
Journal, issue, pagesJ. Mol. Biol., Vol. 292, Page 1-9, Year 1999
Publish dateAug 10, 1999 (structure data deposition date)
AuthorsKallen, J. / Welzenbach, K. / Ramage, P. / Geyl, D. / Kriwacki, R. / Legge, G. / Cottens, S. / Weitz-Schmidt, G. / Hommel, U.
External linksJ. Mol. Biol. / PubMed:10493852
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1cqp:
CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-803:
LOVASTATIN / medication*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / ROSSMANN FOLD / STRUCTURAL BASIS FOR LFA-1 INHIBITION

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