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Structure paper

TitleStructure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 96, Page 9491-9496, Year 1999
Publish dateJun 23, 1999 (structure data deposition date)
AuthorsLi, Y. / Mitaxov, V. / Waksman, G.
External linksProc. Natl. Acad. Sci. USA / PubMed:10449720
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1qss:
DDGTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1qsy:
DDATP-Trapped closed ternary complex of the large fragment of DNA Polymerase I from thermus aquaticus
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1qtm:
DDTTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-DG3:
2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-DDS:
2',3'-dideoxyadenosine triphosphate

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

Source
  • thermus aquaticus (bacteria)
KeywordsTransferase/DNA / PROTEIN-DNA COMPLEX / CLOSED / Polymerase/DNA / Transferase-DNA COMPLEX / DDATP / DDTTP

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