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TitleRelocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
Journal, issue, pagesProtein Eng., Vol. 12, Page 573-579, Year 1999
Publish dateMay 20, 1999 (structure data deposition date)
AuthorsChen, C.C. / Herzberg, O.
External linksProtein Eng. / PubMed:10436083
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1kgg:
STRUCTURE OF BETA-LACTAMASE GLU166GLN:ASN170ASP MUTANT
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (bacteria)
KeywordsHYDROLASE / ANTIBIOTIC RESISTANCE / BETA-LACTAM HYDROLYSIS

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