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| Title | Structure-based design, synthesis, and X-ray crystallography of a high-affinity antagonist of the Grb2-SH2 domain containing an asparagine mimetic. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 42, Page 2358-2363, Year 1999 |
| Publish date | Apr 21, 1999 (structure data deposition date) |
Authors | Furet, P. / Garcia-Echeverria, C. / Gay, B. / Schoepfer, J. / Zeller, M. / Rahuel, J. |
External links | J. Med. Chem. / PubMed:10395476 |
| Methods | X-ray diffraction |
| Resolution | 3 Å |
| Structure data | ![]() PDB-1cj1: |
| Chemicals | ![]() ChemComp-C78: ![]() ChemComp-HOH: |
| Source |
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Keywords | SIGNALING PROTEIN / SIGNAL TRANSDUCTION / SH2 DOMAIN / PHOSPHOTYROSINE |
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