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Structure paper

TitleCrystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition.
Journal, issue, pagesBiochemistry, Vol. 38, Page 7444-7452, Year 1999
Publish dateAug 12, 1998 (structure data deposition date)
AuthorsTaylor, A.B. / Johnson Jr., W.H. / Czerwinski, R.M. / Li, H.S. / Hackert, M.L. / Whitman, C.P.
External linksBiochemistry / PubMed:10360941
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1mfi:
CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-FHC:
2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN / CYTOKINE / MACROPHAGE / INFLAMMATORY RESPONSE / TAUTOMERASE

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