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TitleEngineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
Journal, issue, pagesJ. Mol. Biol., Vol. 289, Page 565-577, Year 1999
Publish dateApr 20, 1999 (structure data deposition date)
AuthorsKent, H.M. / Moore, M.S. / Quimby, B.B. / Baker, A.M. / McCoy, A.J. / Murphy, G.A. / Corbett, A.H. / Stewart, M.
External linksJ. Mol. Biol. / PubMed:10356329
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1qg2:
CANINE GDP-RAN R76E MUTANT
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1qg4:
CANINE GDP-RAN F72Y MUTANT
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • canis lupus familiaris (dog)
KeywordsGTPASE / NUCLEAR TRANSPORT

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